The Trans Directory
Start new page on different from of MTF HRT. mainly the pill section
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content/MTF/MTF forms of HRT.md
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content/MTF/MTF forms of HRT.md
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There are several routes of taking HRT and the main forms are: pills, gels, patches and injections. There are less common forms too that are mainly used in the DIY scene such as Transdermal Estradiol Spray and Sublingual Estradiol Oil Drops.
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diyhrt.info lists a general price range for the more common methods but that is very US targeted and obviously differs for DIY and different health cares so here I will go over a few specific forms, their common dosages/concentrations and any other relevant information on those methods.
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## Pills
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Pills come in two common formulations Estradiol Valerate and Estradiol Hemihydrate.
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the most common concentrations are 1mg and 2mg pills.
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Generally in pill form the bioavailability is low so right off the bat I recommend taking them the sublingual route(placing the pill under your tongue and letting it slowly dissolve).
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Sublingual is around 1.5x more effective at absorbing oestrogen compared to the oral route.[^1]
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[^1]: See DOI: [10.1089/trgh.2023.0138](https://doi.org/10.1089/trgh.2023.0138) for more information. the 1.5x claim is specifically from "Table 4 - Mean Estrone/Estradiol Ratio". Fig 2 is a great visual comparison. this paper can also be found on [[Research Papers]].
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paper name: Comparison of Estrone/Estradiol Ratio and Levels in Transfeminine Individuals on Different Routes of Estradiol